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  • 标题:Invasive pneumococcal disease in Australia, 2003
  • 本地全文:下载
  • 作者:Paul Roche ; Vicki Krause ; Mark Bartlett
  • 期刊名称:Communicable Diseases Intelligence
  • 印刷版ISSN:1447-4514
  • 电子版ISSN:1445-4866
  • 出版年度:2004
  • 卷号:28
  • 期号:4
  • 页码:441-454
  • 出版社:Government Department of Health and Ageing
  • 摘要:There were 2,174 cases of invasive pneumococcal disease (IPD) notifi ed to the National Notifi able Diseases Surveillance System (NNDSS) in Australia in 2003; a rate of 10.9 per 100,000 population. The notifi cation rate varied between states and territories and by geographical region with the highest rates in the north of the country. Invasive pneumococcal disease was reported most frequently in children aged less than two years (98.8 cases per 100,000 population). Enhanced surveillance for IPD in 2003 was carried out in all states and territories, providing additional data on 1,842 (85%) of all notifi ed cases. Rates of IPD in Indigenous Australians were three times the rate in non-Indigenous Australians. There were 125 deaths attributed to IPD resulting in an overall case fatality rate of 6.8 per cent. Seventy-one percent of all pneumococcal isolates serotyped were serotypes in the seven-valent conjugate vaccine and 91 per cent were serotypes in the 23-valent polysaccharide pneumococcal vaccine. The clinical presentation and risk factors for IPD varied between Indigenous and non-Indigenous cases and non-vaccine serotypes occurred more frequently among Indigenous children and adults. Data from three years of surveillance indicate an early impact of the 7-valent vaccine in the target population. Commun
  • 关键词:invasive pneumococcal disease; Streptococcus pneumoniae; surveillance; vaccination
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