文章基本信息

标题：An outbreak of serogroup C meningococcal disease associated with a secondary school
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作者：Priscilla Robinson ; Kath Taylor ; Graham Tallis 等
期刊名称：Communicable Diseases Intelligence
印刷版ISSN：1447-4514
电子版ISSN：1445-4866
出版年度：2001
卷号：25
期号：3
页码：121-125
出版社：Government Department of Health and Ageing
摘要：An outbreak of 3 cases of invasive meningococcal disease occurred in a secondary school on 2 campuses in Victoria.Despite having only one isolate (a C.2a:nst strain), meningococcal DNA was identified by polymerase chain reaction(PCR) in early culture-negative blood specimens of the other 2 cases. Both were subsequently shown by PCR to becapsule serogroup C by PCR. An committee was formed to manage the response to the outbreak. Chemo-prophylaxis was offered to family and children who had been in close contact with the cases. As one strain had beenconfirmed as being of a vaccine-preventable group, vaccination was offered to the whole school community as wellas the families of cases. The direct costs of the outbreak to public health, which would have been identical whateverthe causative serogroup, was $8,178. Vaccine charges accounted for most of the additional $56,941 cost ofvaccinating the target group of 1600 students, staff, and families. No further cases have been associated with thisoutbreak
关键词：surveillance;Neisseria meningitidis; meningococcal disease; antibiotics; penicillin; vaccination