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  • 标题:Australia's last reported case of wild poliovirus infection
  • 本地全文:下载
  • 作者:Margery L Kennett ; Kerri Anne Brussen ; David J Wood
  • 期刊名称:Communicable Diseases Intelligence
  • 印刷版ISSN:1447-4514
  • 电子版ISSN:1445-4866
  • 出版年度:1999
  • 卷号:23
  • 期号:3
  • 页码:77-79
  • 出版社:Government Department of Health and Ageing
  • 摘要:In 1986 tests on faeces collected from a 22 year old Australian born man who had symptoms consistent withpoliomyelitis yielded poliovirus type 3. In a neutralisation test using a panel of monoclonal antibodies the isolatewas identified as wild poliovirus type 3 at that time. After further classification using microneutralisation, nucleicacid probe hybridisation, immunoassay and sequencing carried out in three laboratories between 1994 and 1997,the isolate has been reclassified as 'Sabin-like' with 'wild type' characteristics. This case has been quoted in theliterature as Australia's last case of locally acquired wild poliovirus. Efforts are now being made to identify the truelast case in Australia. This article describes the isolation, identification and further characterisation of this virus.
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