There has been a shift in the workflow at academic biomedical research and clinical care centers to promote more efficient clinical and community implementation of bench discoveries. Strong financial support for this effort is provided by the Clinical and Translational Science Awards (CTSAs) from the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), awarded to about sixty biomedical research institutions constituting the CTSA Consortium 1. CTSAs offer an opportunity to speed the translation of bench discoveries to improved human health by transforming the research enterprise at the local, regional, and national levels. These efforts include large-scale infrastructure projects, institution-wide coordination and provision of services, incentives to facilitate collaboration and team-based science, and education programs designed to train the next generation of researchers.