文章基本信息

标题：Vitamin D and Cardiovascular Disease
本地全文：下载
作者：Vivian Cristina Garcia ; Lígia Araújo Martini
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2010
卷号：2
期号：4
页码：426-437
DOI：10.3390/nu2040426
语种：English
出版社：MDPI Publishing
摘要：Vitamin D insufficiency/deficiency has been observed worldwide at all stages of life. It has been characterized as a public health problem, since low concentrations of this vitamin have been linked to the pathogenesis of several chronic diseases. Several studies have suggested that vitamin D is involved in cardiovascular diseases and have provided evidence that it has a role in reducing cardiovascular disease risk. It may be involved in regulation of gene expression through the presence of vitamin D receptors in various cells, regulation of blood pressure (through renin-angiotensin system), and modulation of cell growth and proliferation including vascular smooth muscle cells and cardiomyocytes. Identifying correct mechanisms and relationships between vitamin D and such diseases could be important in relation to patient care and healthcare policies.
关键词：vitamin D; cardiovascular disease; hypertension