文章基本信息

标题：The sun – our friend or foe?
本地全文：下载
作者：Agnieszka Osmola-Mańkowska ; Wojciech Silny ; Aleksandra Dańczak-Pazdrowska 等
期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2012
卷号：19
期号：4
页码：805-809
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction and objective: Sunlight is the major source of the energy on Earth. Visible light, ultraviolet and infrared radiation are necessary to sustain life on our planet. However, besides the range of positive e ects, such as photosynthesis in plants, warmth, vision, and synthesis of vitamin D, sunlight may also be responsible for negative biologic e ects – sunburn, induction of photodermatoses or carcinogenesis. Ultraviolet is regarded as the major environmental, physical hazard to the human skin.Abbreviated description of the state of knowledge: The acute clinical e ect of ultraviolet involves melanogenesis, i.e. tanning, which protects from sunburn if exposure is overdosed. A single exposure, as well as acute suberythemal irradiation, suppresses sensitization of the contact hypersensitivity. The chronic biological e ects are photoageing and skin cancer, especially squamous cell carcinoma (SCC). Vitamin D synthesis is regarded as a bene t of natural acute and chronic exposure to ultraviolet. Ultraviolet also plays an important role in aetiology of the group of disorders characterized by photosensitivity. On the other hand ultraviolet is a known inducer of immunosuppression in the skin; therefore, phototherapy is a therapeutic option for patients with activation of dermal immunity.Summary: Without sunlight, the existence of life on Earth is not possible. On the other hand, UVR radiation is regarded as representing one of the most important environmental hazards for human skin. For a better understanding of the mechanisms related to the in uence of UVR on human skin, and the most dangerous chronic e ects of carcinogenesis, it is necessary to undertake some protective ac tivities. Moreover, UVR may become our ally in the treatment of selected skin disorders
关键词：ultraviolet radiation; photodermatoses; skin cancer; photoaging; phototherapy; photoprotec tion