文章基本信息

标题：Twice malignant transformation of hypertrophic lichen planus
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作者：Dorota Krasowska ; Katarzyna Kozłowicz ; Małgorzata Kowal 等
期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2012
卷号：19
期号：4
页码：787-789
出版社：Institute of Agricultural Medicine in Lublin
摘要：Lichen planus is a chronic mucocutaneous T-cell-mediated disease, the cause of which remains unknown. The rst case of lichen planus that transformed into squamous cell carcinoma was reported in 1903. The presented study concerns the case of a 62-year-old woman in whom twice malignant transformation of hypertrophic lichen planus in the dorsal part of the left foot developed. Several studies have pointed out the malignant transformation potential of lichen planus. Epidemiological studies from the last 20 years have revealed a malignant transformation rate of 0.27% per year, emphasizing the importance of the clinical follow-up of lichen planus patients
关键词：autoimmune disease; lichen planus; malignant transformations; squamous cell carcinoma.