This article deals with a fluid flow in the pipe junction. The comparison of the pipe junction characteristics obtained from the experiment with the pipe junction characteristics obtained from the numerical modelling using the CFD software will be discussed in this article. All measurements are done for the case of 50 mm diameter of the straight pipe and 20 mm diameter of the adjacent branch with five different angles. There are six possible flow configurations for this pipe junction. Three of them are cases of the flow combination and three of them are cases of the flow division. Only results for the flow combination are presented in this paper.