文章基本信息

标题：Optimal Control Problem of Treatment for Obesity in a Closed Population
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作者：D. Aldila ; N. Rarasati ; N. Nuraini 等
期刊名称：International Journal of Mathematics and Mathematical Sciences
印刷版ISSN：0161-1712
电子版ISSN：1687-0425
出版年度：2014
卷号：2014
DOI：10.1155/2014/273037
出版社：Hindawi Publishing Corporation
摘要：Variety of intervention programs for controlling the obesity epidemic has been done worldwide. However, it is still not yet available a scientific tool to measure the effectiveness of those programs. This is due to the difficulty in parameterizing the human interaction and transition process of obesity. A dynamical model for simulating the interaction between healthy people, overweight people, and obese people in a randomly mixed population is discussed in here. Two scenarios of intervention programs were implemented in the model, dietary program for overweight people with healthy life campaign and treatment program for obese people. Assuming all control rates are constant, disease free equilibrium point, endemic equilibrium point, and basic reproductive ratio () as the epidemic indicator were shown analytically. We find that the disease free equilibrium point is locally asymptotical stable if and only if . From sensitivity analysis of , we obtain that larger rate of dietary program and treatment program will reduce significantly. With control rates are continuous in time, an optimal control approach was applied into the model to find the best way to minimize the number of overweight and obese people. Some numerical analysis and simulations for optimal control of the intervention were shown to support the analytical results.