文章基本信息

标题：Prostatic Injection of Botulinum A Toxin: An Alternative Treatment for Benign Prostatic Hyperplasia
本地全文：下载
作者：Aliasghar Yarmohamadi ; Samira Yaghobi ; Mahmoud Molaee 等
期刊名称：Knowledge & Health Journal
印刷版ISSN：1735-577X
出版年度：2009
卷号：4
期号：1
出版社：Shahroud University of Medical Sciences
摘要：Introduction: We examined the clinical effectiveness of prostate injection of botulinum A toxin in the treatment of BPH. Methods: In this deh1ive study 55 men with BPH who had failed medical treatment and were poor risks for surgery were treated by injection of botulinum A toxin into different parts of the transition zone. Amounts of prostate-specific antigen(PSA) prostate symptom scores quality-of-life index prostate volume postvoid residual urine volume and peak urinary flow rates were recorded and compared for all patients before injection and 3 and 6 months after the injection. Results: The mean patient age was 78±2.5 years. The mean symptom score and quality-of-life index significantly improved after 3 months. Maximal urinary flow rate (Qmax) showed a significant increase after 3 and 6 months of treatment. Postvoid residual urine volume had a significant decrease after 3 and 6 months (P0.05). Prostate volume decreased from 65±8 ml to 59±6 ml within 1 month and to 49±5 ml within 3 months (P
关键词：Prostate Outline a toxin Benign prostatic hyperplasia (BPH)