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标题：Effect of Vit C Supplement on Fasting Blood Glucose and Plasma Lipid Level in Type II Diabetic Patients
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作者：Mehri Delvarianzadeh ; Abbasian ; Piraste Norouzi 等
期刊名称：Knowledge & Health Journal
印刷版ISSN：1735-577X
出版年度：2008
卷号：3
期号：1
出版社：Shahroud University of Medical Sciences
摘要：Introduction: Diabetic people are more at risk of diseases such as vascular, kidneys and eye diseases, compared with normal people. Since Vit C competitively replaces glucose in most chemical reactions; so inhibit on non enzymatic glycosylation such as hemoglobin and lipoproteins, it seems that Vit C can be effective to prevent diabetic complications .In this study effect of Vit C supplements on blood sugar and fats level in type II diabetic patients was investigated. Methods: This study was conducted as a clinical trial using paired random sampling on 136 type II diabetic patients. At first, the patients weights, age, type of diet were recorded .Then their fasting blood glucose (FBS), glycosylated hemoglobin (HbAIC), Cholesterol, triglyceride, HDL and LDL were measured. After that the patients were divided in two randomized groups. The first group (control) was subject of administration of Vit C supplement (1250 mg, 5 times a day, for a period of 3 months) and the second group received placebo. Data were analyzed by paired t- test and SPSS Software. Results: In this study most of patients were women (62.2% of control group and 64.7% of placebo group). The mean age between the control group and placebo group were reported 51.2 ± 6.8 and 50.37± 9.71 years respectively. At the end of study , after 3 months of administration of Vit C supplement to control group, the mean concentration of FBS, LDL triglyceride Cholesterol and glycosylated hemoglobin has been reduced significantly with respect to the placebo group and the mean value of HDL has been increased as well. Conclusion: The finding shows that Vit C supplements might reduce the amount of glucose, lipids and glycosylated hemoglobin in patients with type 2 diabetes. Therefore, its consumption in diabetic patients can be recommended and as a result patient complications will be significantly reduced.
关键词：Diabetes type II Vit C Fasting blood glucose; Lipid Glycosylated Hemoglobin