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  • 标题:Metformin, aging and cancer
  • 本地全文:下载
  • 作者:Olga Moiseeva ; Xavier-Deschênes-Simard ; Michael Pollak
  • 期刊名称:Aging
  • 出版年度:2013
  • 卷号:5
  • 期号:5
  • 页码:330-331
  • 出版社:U.S.Department of Health & Human Service
  • 摘要:Many cancers are associated with aging [1]. Metformin, a widely used antidiabetic drug, has been linked to a reduced cancer incidence in some retrospective, hypothesis-generating studies [2]. Since cancer and aging may share certain molecular processes, it is plausible that metformin may prevent cancer by acting on the aging process. Consistent with this idea, several studies report a life span extension in animal models after treatment with metformin [3].
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