文章基本信息

标题：Colored Stochastic Petri Nets for Modeling Complex Biological Systems
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作者：Fei Liu ; Ming Yang
期刊名称：International Journal of Hybrid Information Technology
印刷版ISSN：1738-9968
出版年度：2013
卷号：6
期号：5
出版社：SERSC
摘要：The stochastic modeling of biological systems is gaining more and more attention when stochastic fluctuations need to be described. On the other hand, the biological systems under investigation become much more complex than before. Traditional modeling methods like stochastic Petri nets do not easily scale and thus become difficult to tackle this situation. This paper aims to present a colored stochastic Petri net approach for systems biology to modeling complex biological systems. Specifically, this paper describes a type of biochemically-interpreted colored stochastic Petri nets and their extensions and analysis techniques for systems biology and illustrates their applications using Ca2+release sites that consist of a set of coupled Ca2+channels
关键词：colored stochastic Petri nets; systems biology; complex biological systems; ;Ca;2+ ;channels; Ca;2+ ;release sites