文章基本信息

标题：Silent ACTHoma: A subclinical presentation of Cushing’s disease in a 79 year old male
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作者：Meenal Malviya ; Navneet Kumar ; Naseer Ahmad 等
期刊名称：International Journal of Collaborative Research on Internal Medicine & Public Health
电子版ISSN：1840-4529
出版年度：2013
卷号：5
期号：8
出版社：DRUNPP Sarajevo
摘要：Pituitary adenomas are mostly benign tumors which may be clinically functioning or non-functioning. ACTH secreting tumors causing Cushing's disease are detected in0.7 to 2.4 per million individuals per year. Most of the cases reported on such ACTHomas are microadenomas (<10mm) and very few macroadenomas (>10mm). We report an unusual case of 79 year-old elderly patient presenting with subclinical Cushing's disease due to pituitary macroadenoma (ACTHoma) found incidentally. It raises many possibilities of biochemical nature of hormone in such patients or early degradation of hormone. It certainly brings to our attention that more clinical research is needed to find causes of subclinical Cushing's disease
关键词：pituitary macroadenomas; Corticotroph adenomas; microadenomas; hypercortisolism