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标题：Screening of pregnant women for iodine deficiency and iron deficiency duringearly gestation in Vadodara
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作者：Kejal Joshi ; Sirimavo Nair ; M. G. R. Rajan 等
期刊名称：Healthline
印刷版ISSN：2229-337X
出版年度：2012
卷号：3
期号：1
出版社：Indian Association of Preventive and Social Medicine, Gujarat
摘要：BACKGROUND: Over the past decade, there hasbeen increasing focus on iodine deficiency duringpregnancy, yet 38 million newborns in developingcountries every year remain unprotected from thelifelong consequences of brain damage associatedwith iodine deficiency. Pregnant women are ofteniron deficient and iron deficiency has adverseeffects on thyroid metabolism. Hence, to preventboth the mother and baby from the consequencesof iodine and iron deficiency, pregnant womenshould be screened as early as possible.OBJECTIVE: To screen pregnant women foriodine deficiency and iron deficiency during earlygestation. Methods: Pregnant women (¡Ü15 weeks)attending antenatal clinic (January¨CMarch 2010)in Jamnabai General Hospital, Vadodara wereenrolled for the study. Urine and blood sampleswere collected from 225 pregnant women forestimation of urinary iodine, haemoglobin andthyroid hormones.RESULTS: Out of the total population (n=225),only 52 % had normal thyroid hormone levels.Median urinary iodine concentration (UIC) was274.82 ¦Ìg/l and 21.6 % of the population had UIC< 150 ¦Ìg/l. Mean TSH and FT4was 2.29¡À1.6¦ÌIU/ml and 10.20¡À2.5 pmol/dl, respectively, with22 % pregnant women having TSH >2.5 ¦ÌIU/mland normal FT4(subclinical hypothyroidism), 15% having FT4<8.36 pmol/dl and normal TSH(hypothyroxenemia) and 11 % having both (overthypothyroidism). Mean haemoglobin was foundto be 9.2¡À1.1 g/dl. Out of the total populationscreened 93 % had haemoglobin levels below 11g/dl. Conclusion: Iodine and iron nutrition inpregnant women (LIG) of Vadodara is observedto be sub optimal, which may compromise thepotential development for adequate mental andpsychomotor development of the offspring duringgestation.
关键词：pregnancy; iron deficiency; iodine;deficiency