文章基本信息

标题：Porcine Circovirus 2: Immunopathogenesis and Recent Developments in Vaccines
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作者：Abelardo Silva Júnior ; Otávio Valério de Carvalho ; Luiz Henrique Silva Bulos 等
期刊名称：World Journal of Vaccines
印刷版ISSN：2160-5815
电子版ISSN：2160-5823
出版年度：2012
卷号：2
期号：2
页码：96-104
DOI：10.4236/wjv.2012.22013
出版社：Scientific Research Publishing
摘要：Porcine circovirus 2 (PCV2) is currently considered an important etiologic agent of swine and its infection has potentially serious economic impact on the swine industry worldwide. This virus is frequently associated with postweaning multisystemic wasting syndrome (PMWS), and also with other clinical conditions such as porcine dermatitis and nephropathy syndrome (PDNS), late-term abortions, reproductive failure in sows, proliferative and necrotizing pneumonia and congenital tremors. The term porcine circovirus-associated disease (PCVAD) is currently used to refer to any of these diseases when they are associated with PCV2 infection. The PCV2 was recognized as a pathogen in 1997, and many questions regarding its biology and pathogenesis remain unanswered. Currently, some studies have shown the production of new vaccine candidates and field efficacy testing of commercial vaccines. This review discusses some major points concerned with immunopathogenesis and vaccines for PCV2 infection.
关键词：Porcine circovirus 2; Vaccine; Immunopathogenesis