文章基本信息

标题：Is there any role of glucose-6-phosphate dehydrogenase in obesity induced metabolic disorder
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作者：Manisha Sankhla ; Keerti Mathur ; Jai Singh Rathor 等
期刊名称：Health
印刷版ISSN：1949-4998
电子版ISSN：1949-5005
出版年度：2012
卷号：4
期号：12A
页码：1530-1536
DOI：10.4236/health.2012.412A219
出版社：Scientific Research Publishing
摘要：The present study was designed to explore the possible mechanism of obesity associated metabolic syndrome. 150 subjects (120 men and 30 women) in the age-group of 17 - 26 years were studied. Body Mass Index and Waist-to-Hip Ratio were taken as a measure of generalized obesity and abdominal adiposity. The serum concentration of glucose-6-phosphate dehydrogenase increased with increasing levels of Body Mass Index and was found to be significant in obese subjects (Body Mass Index ≥ 30.0 kg/m²) and more so in the obese subjects with abdominal adiposity (p = 0.002) as compared to normal-weight subjects. Karl Pearson coefficient of correlation revealed a significant positive correlation of glucose-6-phosphate dehydrogenase with Body Mass Index (r = 0.499; p
关键词：Obesity; Abdominal Adiposity; Oxidative Stress; Glucose-6-Phosphate Dehydrogenase; Adiponectin