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标题：Visfatin Gene Responses to 8 Weeks of Treadmill Running with or without Pistachio atlantica Liquid Extraction in Female Rat Tissues
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作者：Abbass Ghanbari-Niaki ; Navabeh Zare Kookandeh ; Saleh Rahmati Ahmadabad 等
期刊名称：Food and Nutrition Sciences
印刷版ISSN：2157-944X
电子版ISSN：2157-9458
出版年度：2012
卷号：3
期号：8
页码：1144-1149
DOI：10.4236/fns.2012.38150
出版社：Scientific Research Publishing
摘要：Visfatin, a novel adipokine, was revealed to be associated with obesity and to have insulin mimetic effect that is highly expressed in visceral adipose tissue. The aim of this study was to determine the liver and kidney visfatin relative gene expression. Twenty wistar rats (6-8 weeks old and 125-135 g weight) were used. Animals were randomly assigned into saline-control (SC), saline-training (ST), and Baneh-control (BC), and Baneh-training (BT). Training groups was given exercise on a motor-driven treadmill at 25 m/min (0% grade) for 60 min/day and 5 days/week for eight weeks. Subjects were fed oral, with Baneh extraction and saline for four weeks. Visfatin relative gene expression was detected by Real-time PCR method. Also plasma was collected for glucose measurements. Results demonstrated that Baneh extraction significantly increase visfatin relative gene expression in liver (P < 0.002) and increase not significantly in kidney tissue. Exercise training significantly reduce visfatin relative gene expression in liver (P < 0.042), and reduce not significantly in kidney tissue. Plasma and liver glucose level increases by Baneh. Exercise training decreses visfatin relative gene expression and Baneh increases visfatin relative gene expression in liver and kidney. Also Baneh can increases plasma glucose and liver glucose and glycogen concentration probably due to high fatty acid and component.
关键词：Visfatin; Female Rats; Treadmill Exercise; Pistachia atlantica