摘要:The present investigation was carried out to study the anti-bacterial activity of ethanolic and methanolic extracts of stem, berries and whole plant of Solanum nigrum. The antibacterial activity was detected against Bacillus subtilis, Escherichia coli, Klebsiella pneumonia and Pseudomonas aeruginosa. Solanum nigrum plant extracts of, 10ìg, 50ìg and 100ìg were taken as per CLSI standards. The zones of inhibitions obtained were recorded and analyzed against standard control streptomycin. The methanolic extracts were showed highest antibacterial activity than ethanolic extracts. In both extracts, whole plant extract showed potential anti-bacterial activity than stem and berries. The results indicate that the whole plant extracts of Solanum nigrum may recommend to use in preparation of herbal drugs.