The multi-proxy evidence from Lake Zeribar indicates the possible impact of the Younger Dryas on Western Iran. By the end of this episode, the region was affected by rising temperatures and ensuing environmental enrichment, which could have resulted in changes in the settlement pattern from mobility to more sedentism c. 9500 BC. It is proposed that semi-sedentism led to population growth and ensuing food management in the region, which finally encouraged people to domesticate plants and animals around 8000 BC. This paper will briefly discuss the three ‘why’, ‘how’ and ‘when’ questions in investigating the Neolithisation process in western Iran.