首页    期刊浏览 2024年12月13日 星期五
登录注册

文章基本信息

  • 标题:Acute meningoencephalitis in a patient with systemic lupus erythematosus
  • 本地全文:下载
  • 作者:Perić-Popadić Aleksandra ; Bogić Mirjana ; Tomić-Spirić Vesna
  • 期刊名称:Vojnosanitetski pregled
  • 印刷版ISSN:0042-8450
  • 出版年度:2013
  • 卷号:70
  • 期号:7
  • 页码:688-692
  • DOI:10.2298/VSP1307690P
  • 出版社:Military Medical Academy, INI
  • 摘要:

    Introduction. Infections in patients with systemic lupus erythematosus (SLE) are a significant factor of morbidity and mortality. Although central nervous system infections, including septic meningitis, are rare in patients with SLE, they can be significant causes of mortality inspite of the prompt and accurate diagnosis and proper management. Case report. We presented a woman with the diagnosis of SLE and diffuse proliferative lupus nephritis. Because of disease activity we introduced cytostatic immunosuppressive therapy, cyclophosphamide and then azathioprine. Meningoencephalitis, staphylococcal sepsis and abscess of the brain, with resulting seizures developed. Conclusion. This case alerts to the need of careful examination of patients with SLE, collection of adequate cultures and evaluation of predisposition towards ifnections, before the introduction of immunosuppressants due to potentially fatal infection.

  • 关键词:lupus erythematosus; systemic; central nervous system; infections; meningoencephalitis; immunosuppression
国家哲学社会科学文献中心版权所有