文章基本信息

标题：Association of Human Papilloma Virus Infection and Oral Squamous Cell Carcinoma in Bangladesh
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作者：Akhter, Mahmuda ; Ali, Liaquat ; Hassan, Zahid 等
期刊名称：The Journal of Health, Population and Nutrition
印刷版ISSN：1606-0997
电子版ISSN：2072-1315
出版年度：2013
卷号：31
期号：1
页码：65-69
出版社：International Centre for Diarrhoeal Disease Research Bangladesh
摘要：Oral squamous cell carcinoma is the sixth most common malignancy worldwide. In Bangladesh, it comprises 20% of the whole body malignancies. Several studies found that 15% to 25% of oropharyngeal cancer cases are associated with human papilloma virus (HPV). This study is done to find the association of human papilloma virus subtypes, particularly HPV type 16 and HPV type 18, with the oral squamous cell carcinoma in Bangladeshi patients. In total, 34 diagnosed patients of oral squamous cell carcinoma were included in the study. Extracted DNA from the cancerous tissues was checked for PCR reaction to detect the subtypes of human papilloma virus. Data of the present study suggest that oral squamous cell carcinoma are almost absent in Bangladeshi patients with human papilloma virus, particularly HPV 16 and 18.
关键词：Human papilloma virus (HPV); HPV type 16; HPV type 18; Oral cancer; Polymerase chain reaction; Bangladesh