文章基本信息

标题：A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals
本地全文：下载
作者：Hisashi Moriguchi ; Yue Zhang ; Makoto Mihara 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2012
卷号：2
DOI：10.1038/srep00280
出版社：Springer Nature
摘要：
Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).
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