文章基本信息

标题：A Guide for Mitochondrial DNA Analysis in Non-Human Forensic Investigations
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作者：Filipe Pereira ; João Carneiro ; Barbara van Asch 等
期刊名称：Open Forensic Science Journal
印刷版ISSN：1874-4028
出版年度：2010
卷号：3
页码：33-44
DOI：10.2174/1874402801003010033
出版社：Bentham open
摘要：
In recent years, mitochondrial DNA (mtDNA) typing has become established as a powerful tool for forensic investigations. The sequencing of mtDNA is now a standard laboratory procedure for the examination of degraded casework samples of human origin, with unique advantages over nuclear DNA profiling systems. Nonetheless, the use of mtDNA in non-human forensic science has only recently gained attention, with applications in the profiling of ‘silent witnesses’ of crimes, traceability of food products and control of illegal trade of endangered species or drugs, among others. This review briefly describes some important features of mtDNA with relevance for forensic testing in different taxonomic groups and suggests appropriate laboratorial and analytic procedures to avoid erroneous interpretations. It is imperative to merge a solid knowledge of mitochondrial genetics with rigorous methods of error prevention in order to permit the full approval of non-human mtDNA profiling in routine forensic work.