文章基本信息

标题：Scientific Opinion on the safety evaluation of the substance, N-(2-aminoethyl)ethanolamine, CAS No. 111-41-1, for use in food contact materials
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作者：Ulla Beckman Sundh ; Mona-Lise Binderup ; Leon Brimer 等
期刊名称：EFSA Journal
印刷版ISSN：1831-4732
出版年度：2012
卷号：10
期号：4
DOI：10.2903/j.efsa.2012.2653
出版社：European Food Safety Authority (EFSA), Parma
摘要：This scientific opinion of EFSA deals with the risk assessment of the co-monomer N-(2-aminoethyl)ethanolamine (CAS No 111-41-1, Ref. No 35284 and FCM substance No 262). The CEF Panel concluded that the use of N-(2-aminoethylamino)ethanol in manufacturing of can coatings in direct contact with food does not raise a safety concern for the substance itself if migration does not exceed 0.05 mg/kg food. The Panel, however, noted that many oligomers are formed during the manufacturing process which may migrate into the food. Only limited information was provided on the identities of the oligomers in the fraction below 1000 Da. Further structural and quantitative information is needed for a conclusion to be drawn concerning genotoxicity or other toxicity end points of the oligomeric fraction. The toxicological data needed will depend on the identity and level of migration of the oligomers in the food.
关键词：N-(2-aminoethyl)ethanolamine; CAS No 111-41-1; Ref. No 35284; FCM substance No 262; Food contact materials; Coatings; Safety assessment; Evaluation