文章基本信息

标题：Scientific Opinion on Flavouring Group Evaluation 87 Revision 1 (FGE.87Rev1): Consideration of bicyclic secondary alcohols, ketones and related esters evaluated by JECFA (63^rd meeting) structurally related to bicyclic secondary alcohols, ketones and related esters evaluated by EFSA in FGE.47 (2008)
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作者：Ulla Beckman Sundh ; Mona-Lise Binderup ; Leon Brimer 等
期刊名称：EFSA Journal
印刷版ISSN：1831-4732
出版年度：2012
卷号：10
期号：2
DOI：10.2903/j.efsa.2012.2564
出版社：European Food Safety Authority (EFSA), Parma
摘要：The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives (the JECFA), and to decide whether further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. The present consideration concerns a group of 17 bicyclic secondary alcohols, ketones and related esters evaluated by the JECFA at the 63^rd meeting in 2004. This revision of FGE.87 is made due to consideration of two additional substances [FL-no: 02.100 and 02.101] compared to previous version. Additionally, new information on EU production volume on two substances and information on stereoisomeric composition for 13 substances are also included. The substances were evaluated through a stepwise approach that integrates information on structure-activity relationships, intake from current uses, toxicological threshold of concern, and available data on metabolism and toxicity. The Panel agrees with the application of the Procedure as performed by the JECFA for all 17 substances considered in this FGE and agrees with the JECFA conclusion, “No safety concern at estimated levels of intake as flavouring substances” based on the MSDI approach. Besides the safety assessment of these flavouring substances, the specifications for the materials of commerce have also been considered for the substances evaluated through the Procedure and for two substances, [FL-no: 02.100 and 02.101], information on the stereoisomeric composition is lacking.
关键词：Flavouring; food safety; Bicyclic secondary alcohols; ketones and related esters; JECFA; secondary alicyclic saturated alcohols; secondary alicyclic unsaturated alcohols; FGE.47; FGE.87