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标题：Scientific Opinion on the safety and efficacy of Actisaf Sc47 (Saccharomyces cerevisiae) as a feed additive for rabbits for fattening and non food-producing rabbits
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作者：Gabriele Aquilina ; Georges Bories ; Andrew Chesson 等
期刊名称：EFSA Journal
印刷版ISSN：1831-4732
出版年度：2012
卷号：10
期号：1
DOI：10.2903/j.efsa.2012.2531
出版社：European Food Safety Authority (EFSA), Parma
摘要：The additive Actisaf Sc47 is a microbiological feed additive consisting only of dried cells of Saccharomyces cerevisiae. The applicant has requested the re-evaluation of the product when used as a zootechnical additive (functional group: gut flora stabilisers) in diets for rabbits for fattening and the extension of use in diets for non food-producing rabbits at the inclusion rate of 5 x 10⁹ CFU/kg feedingstuffs. S. cerevisiae is a species which is considered by EFSA to be suitable for the QPS approach to safety assessment. As the identity of the active agent has been established, the use of Actisaf Sc47 can be presumed safe for the target species, consumers and the environment. Actisaf Sc47 is non-irritant to skin. Given the absence of particles of inhalable size and the virtual absence of dust, exposure and therefore sensitisation via a respiratory route is not to be expected. Three trials performed with weaned rabbits showed the potential of Actisaf Sc47 to reduce mortality when used in diets at a dose of 5 x 10⁹ CFU/kg feed. A similar effect can be expected in non food-producing rabbits.
关键词：Zootechnical additive; gut flora stabiliser; Actisaf Sc47; Saccharomyces cerevisiae; rabbits for fattening; non food-producing rabbits; safety; efficacy