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  • 标题:Increased Isolation and Characterization of Shigella sonnei Obtained from Hospitalized Children in Tehran, Iran
  • 本地全文:下载
  • 作者:Ranjbar, Reza ; Dallal, Mohammad M. Soltan ; Talebi, Malihe
  • 期刊名称:The Journal of Health, Population and Nutrition
  • 印刷版ISSN:1606-0997
  • 电子版ISSN:2072-1315
  • 出版年度:2008
  • 卷号:26
  • 期号:4
  • 页码:426-430
  • 出版社:International Centre for Diarrhoeal Disease Research Bangladesh
  • 摘要:Shigella flexneri has been the most frequent cause of shigellosis in children in Iran. To evaluate the changes in frequency of serogroups, 302 Shigella species were isolated in 2003 from hospitalized children, aged less than 12 years, with acute diarrhoea in Tehran, Iran. The number of collected S. sonnei, S. flexneri, S. boydii, and S. dysenteriae isolates was 178 (58.9%), 110 (37.4%), 10 (3.3%), and 4 (1.3%) respectively. Most (94%) S. sonnei isolates were resistant to co-trimoxazole. They were, however, relatively or completely sensitive to 15 commonly-used antibiotics. The extracted plasmids showed 12 different profiles with two closely-related patterns constituting 70% of the total isolates. Ribotyping, using PvuII, HindIII or SalI restriction enzymes, generated a single pattern for all S. sonnei isolates. Data suggest that S. sonnei has become the predominant serogroup in children in the hospitals of Tehran.
  • 关键词:Antibiotic resistance; Antibiotics; Drug resistance, Microbial; Dysentery, Bacillary; Ribotyping; Shigella sonnei; Iran
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