文章基本信息

标题：A Study of Antifungal and Antiafl atoxigenic Action of Newly Synthesized Analogues of Dehydroacetic Acid
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作者：Lejla, Duarković ; Blažinkov, Mihaela ; Sikora, Sanja 等
期刊名称：Croatian Journal of Food Technology, Biotechnology and Nutrition
印刷版ISSN：1847-3423
电子版ISSN：1847-7461
出版年度：2010
卷号：5
期号：3-4
页码：127-135
出版社：Hrvatsko društvo prehrambenih tehnologa, biotehnologa i nutricionista
摘要：Mycelial growth and afl atoxin B1 accumulation by toxigenous mould Aspergillus flavus were inhibited by dehydroacetic acid and its newly synthesized analogues, 4-hydroxy-3-(p-toluoyl)-6-(p-tolil)-2H-yrane-2-one (DHT) and 5-Bromo-4-hydroxy-3-(p-toluoyl)-6-(p-tolil)-2Hpyrane-2-one (BrDHT) during the growth of investigated mould on solid substrate (soy-beans). Experiments were carried out in a stationary culture at 20 0C and 30 0C, respectively, during 21 days. Mycelial growth (biomass dry weight) was determined by measuring the chitin content and concentration of afl atoxin B1 (AFB1) was quantitated by HPLC. Concentrations of DHA and DHT of 0.1 and 0.2 μg x g-1 of substrate were stimulated, but concentrations higher than 0.5 μg x g-1 of these compounds, mould growth and AFB1 accumulation partially inhibited. In experiments with 0.2 μg x g-1 of BrDHT mould growth and AFB1 accumulation were inhibited completely depending on the time and temperature of cultivation.
关键词：toxigenous moulds; aflatoxin B1; dehydroacetic acid; chitin; HPLC