文章基本信息

标题：Intravascular Lymphoma and Thyroid Gland
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作者：Katalinić, Darko ; Valković, Toni ; Lučin, Ksenija 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2006
卷号：30
期号：1
页码：239-241
出版社：Hrvatsko antropološko društvo
摘要：Intravascular lymphoma (IVL) is a rare disease characterized by the proliferation of neoplastic cells in the small blood vessels that frequently goes undiagnosed until the time of autopsy. The neoplastic cells are usually of B-cell origin. The clinical course was examined to determine factors that would facilitate antemortem diagnosis. IVL is observed with clinical, histopathological and immunohystochemical methods. This is a unique case because the thyroid gland is a rare place for IVL. Accent is given on immunohystochemical methods and tissue biopsy in the differential diagnosis of IVL when nervous system and thyroid gland dysfunction occur. This report indicates that micro-ecosystem of multinodular goitrous might influence the expression of chemokines and/or adhesion moleculs on endothelial and lymphoma cells, leading to heavy infiltration of thyroid gland. Concurrently, that may guide the physician to tissue biopsy facilitating antemortem diagnosis and institution of appropriate therapy.
关键词：intravascular lymphoma; thyroid gland; tissue biopsy; immunohystochemical methods; chemokines