文章基本信息

标题：Alterations in the Masseter Muscle and Plasma IL-6 Level Following Experimentally Induced Occlusal Interference and Chronic Stress – A Study in Rats
本地全文：下载
作者：Simonić-Kocijan, Sunčana ; Uhač, Ivone ; Tariba, Petra 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2012
卷号：36
期号：2
页码：651-655
出版社：Hrvatsko antropološko društvo
摘要：This study was undertaken to examine the alteration of masseter and plasma interleukin-6 after inducing occlusal interference and chronic stress. Male Wistar rats were submitted to chronic stress procedure, exposed to occlusal interference, or exposed to both mentioned procedures. Whole blood and masseter tissue were collected to determine interleukin-6 level, measured by means of ELISA. Masseter pain was evaluated using the orofacial formalin test. Masseter interleukin- 6 level was significantly higher in animals submitted to combination of occlusal interference and chronic stress than in the control group (p interleukin-6 level (r=0.5741; p groups (p>0.05), as well as no correlation with pain (p>0.05). Combination of occlusal interference and chronic stress leads to strong local reaction characterized by high levels of masseter interleukine-6. High concentrations of muscle interleukin-6 and its correlation with pain point to inflammatory background of masticatory muscle pain.
关键词：dental occlusion; interleukin-6; masseter muscle; orofacial pain; stress; psychological