文章基本信息

标题：Salivary Analytes in Patients with Oral Squamous Cell Carcinoma
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作者：Nola Fuchs, Petra ; Rogić, Dunja ; Vidović-Juras, Danica 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2011
卷号：35
期号：2
页码：359-362
出版社：Hrvatsko antropološko društvo
摘要：Literature data indicates that measurement of certain salivary constituents might serve as a useful diagnostic/prognostic tool in the patients with oral squamous cell carcinoma (OSCC). In 24 patients with OSCC (60±2.5yrs) and in 24 controls (24±3.7yrs) we have determined levels of salivary magnesium, calcium, copper, chloride, phosphate, potassium, sodium, total proteins and amylase. Sodium, potasium and chloride were determined by indirect potentiometry whereas copper, magnesium and phosphate were determined by atomic absorption spectrophotometry. Total proteins were determined by pyrogalol colorimetric method. Amylase levels were determined by continued colorimetric method. Statistical analysis was performed by use of c2 test and Spearman´s correlation test. The results of this study indicate that the concentrations of sodium and chloride were significantly elevated in patients with OSCC when compared to the controls. However, level of total protein was significantly decreased when compared to the healthy controls. Furthermore, there was a negative correlation between alcohol consumption and total protein concentration in patients with oral carcinoma. We might conclude that in patients with OSCC increased salivary sodium and chloride might reflect their overall dehydration status due to alcohol consumption rather than consequence of OSCC iteself.
关键词：oral squamous cell carcinoma; saliva