文章基本信息

标题：CT Perfusion and Noncontrast CT in Acute Ischemic Stroke Diagnosing – Is there Influence on early Thrombolytic Therapy Outcome?
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作者：Janković, Stipan ; Pavičić Ivelja, Mirela ; Kolić, Krešimir 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2010
卷号：34
期号：4
页码：1391-1396
出版社：Hrvatsko antropološko društvo
摘要：The objective of this study was to compare noncontrast computed tomography (NCCT) and computed tomography perfusion (CTP) in early diagnosis of acute ischemic stroke and to define influence of these diagnostic procedures on early outcome of thrombolytic therapy (TLTH). The study included 45 patients, 35 patients submitted to NCCT and CTP and 10 patients who underwent only NCCT, before CTP was introduced. Based on the National Institute of Health Stroke Scale (NIHSS) score we compared early outcome of patients who received TLTH after NCCT only (group 1) with the early outcome of patients who received TLTH following NCCT and CTP (group 2). Statistically significant difference was found in acute stroke diagnosing between CTP and NCCT (p=0.002). There were no statistically significant differences in TLTH early outcome between group 1 and group 2. In conclusion, CTP should be done regulary in patients presenting with acute ischemic stroke symptoms. More research needs to be done in defining exact influence of CTP implementation on the TLTH outcome.
关键词：stroke; computed tomography; perfusion; penumbra; thrombolytic therapy