文章基本信息

标题：Vascular Endothelial Growth Factor in Aqueous Humor of Patients with Perforative Eye Injuries
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作者：Merlak, Maja ; Kovačević, Damir ; Balog, Tihomir 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2008
卷号：32 - Supplement 2
期号：2
页码：33-37
出版社：Hrvatsko antropološko društvo
摘要：Considering that VEGF is the key factor for angiogenesis stimulation, we wanted to establish if VEGF level is increased in aqueous humor of patients with open globe eye injury. The study included 20 patients with open globe injury. During the surgery, aqueous humor samples were taken out and VEGF levels were measured by ELISA. VEGF levels were significantly higher in the aqueous humor of patients with open globe eye injury and uveitis, in patients with wound bigger than 2 mm and in patients where from injury to surgery passed more than 4 hours. VEGF levels were also higher, but not significantly, in patients with intrabulbar foreign body. Considering that VEGF levels were significantly higher in patients with open globe eye injury with uveitis, wound larger than 2 mm and in patients where from injury to surgery passed more than 4 hours, anti VEGF therapy might have application in these conditions.
关键词：vascular endothelial growth factor; aqueous humor; perforative eye injury