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标题：Trabeculectomy with Mitomycin C in Glaucoma Associated with Uveitis
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作者：Novak-Lauš, Katia ; Mandić, Zdravko ; Iveković, Renata 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2005
卷号：29 - Supplement 1
期号：1
页码：17-20
出版社：Hrvatsko antropološko društvo
摘要：The patients with uveitic glaucoma are at high risk for failure following drainage surgery because of young age of these patients, preoperative long-term control of inflammation and postoperative complications. Twenty-two trabeculectomies performed in 22 patients with uveitic glaucoma were retrospectively evaluated to analyze the effect of intraoperative application of mitomycin C (MMC). Success rates, postoperative levels of intraocular pressure (IOP) and postoperative complications were studied. After a mean follow-up of 10.6 months (range, 5–28 months), 15 patients (68.2%) achieved IOP of 21mmHg or less without antiglaucoma medications. There were statistically significant reduction in IOP postoperatively during the period studied (p detachment (9.1%), shallow anterior chamber (9.1%), hyphema (13.6%), macular edema (4.5%) and raised IOP (27.3%). Late postoperative complications included exacerbation of uveitis (4.5%), macular edema (4.5%), cataract (22.7%) and raised IOP (31.8 %). The eyes with raised IOP needed additional antiglaucoma medication. The results of this retrospective and uncontrolled study suggest that intraoperative application of MMC may be a good option for enhancement of short-term trabeculectomy success rates in patients with uveitic glaucoma.
关键词：trabeculectomy; mitomycin C; uveitic glaucoma