文章基本信息

标题：Tuberculosis in HIV-Infected Patients in Croatia between 1986 and 2005
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作者：Puljiz, Ivan ; Begovac, Josip
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2006
卷号：30 - Supplement 2
期号：2
页码：53-58
出版社：Hrvatsko antropološko društvo
摘要：A retrospective medical chart review was performed on 65 HIV-infected patients with tuberculosis hospitalized between 1986 and 2006 at the University Hospital for Infectious Diseases »Dr Fran Mihaljevi}«, Zagreb. Thirty two patients presented with pulmonary involvement, 13 with extrapulmonary, and 20 patients had disseminated tuberculosis. Forty five patients had an abnormal chest X-ray. Mycobacterium tuberculosis was identified in 35 (53.9%) patients. Ten (15.3%) of 65 patients had already been receiving antiviral therapy, while another 31 (47.7%) initiated antiviral therapy after antituberculosis therapy. Tuberculosis-associated immune reconstitution inflammatory syndrome was observed in 11/27 (40.7%) patients. Forty one patient received the standard six month course of antituberculous therapy, while in 12 patients the therapy was prolonged. Twenty one patient (32%) experienced an adverse event to antituberculosis drugs. Twelve patients died (18.5%). After the introduction of highly active antiviral therapy (HAART) the mortality decreased. The incidence of tuberculosis in HIV-infected patients in Croatia is increasing, and tuberculosis is still an important opportunistic infection in our HIV-infected patients.
关键词：Croatia; M. tuberculosis; HIV; AIDS; immune reconstitution inflammatory syndrome