文章基本信息

标题：Seroprevalence of Herpes Simplex Virus Type 2 in Adult HIV-Infected Patients and Blood Donors in Croatia
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作者：Đaković Rode, Oktavija ; Židovec Lepej, Snježana ; Begovac, Josip 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2008
卷号：32
期号：3
页码：693-695
出版社：Hrvatsko antropološko društvo
摘要：The present study estimates herpes simplex virus type 2 (HSV-2) seroprevalence and evaluates its association with age, sex, human herpesvirus type 8 (HHV-8) and human immunodeficiency virus (HIV) among adults in Croatia. A cross-sectional survey included 166 HIV-infected patients and 219 blood donors. Antibodies against HSV-2 were determined by enzyme immunoassays based on gG2 recombinant glycoprotein. HSV-2 seroprevalence was 45.8% in HIV-infected patients and 8.7% in blood donors (p seropositivity were HIV infection (OR 11.0; 95% CI 5.93–20.41), female gender (OR 2.28; 95% CI 1.22–4.26), older age (OR 3.93; 95% CI 2.74–7.11), and HHV-8 seropositivity (OR 2.72; 95% CI 1.09–6.75). Understanding the epidemiology of HSV-2 is a critical first step in designing interventions to decrease HSV-2 and HIV transmission. The association of HSV-2 with HIV infection and HHV-8 antibodies suggests a similar transmission route.
关键词：HSV-2; Croatia; HIV; blood donors; HHV-8; seroprevalence