The Tangsa tribe is one of the tribes of Arunachal Pradesh which is home to 26 major tribes. The Tangsa people are residing in different circles, in and around Changlang township of the Changlang district of Arunachal Pradesh, India. The Changlang district with its headquarters at Changlang was created on 14 November, 1987 by carving out from Tirap district. The word Tangsa is a common name given to a tribe inhabiting this region. The term “Tangsa”, is related with the word Tangshang in Mayanmar (Burma), and it denotes a community of many people in Changlang and Tirap district of Arunachal Pradesh, parts of Tinsukia district of Assam in north east India, and across the border in Sagaing region of Myanmar. The term Tangsa is derived from ‘Tang’ (high land) and ‘sa’ (son) and hence means ‘people of highland’. There are many sub-tribes or group within Tangsa. In this paper an attempt is being made to examine the present blood frequency distribution of Tangsa tribe and compared it with past study of ten tribes.