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  • 标题:Intrinsic reaction-cycle time scale of Na+,K+-ATPase manifests itself in the lipid–protein interactions of nonequilibrium membranes
  • 本地全文:下载
  • 作者:Hélène Bouvrais ; Flemming Cornelius ; John H. Ipsen
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2012
  • 卷号:109
  • 期号:45
  • 页码:18442-18446
  • DOI:10.1073/pnas.1209909109
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Interaction between integral membrane proteins and the lipid-bilayer component of biological membranes is expected to mutually influence the proteins and the membrane. We present quantitative evidence of a manifestation of the lipid-protein interactions in liposomal membranes, reconstituted with actively pumping Na+,K+-ATPase, in terms of nonequilibrium shape fluctuations that contain a relaxation time, {tau
  • 关键词:sodium pump reconstituted in giant vesicles ; vesicle fluctuation analysis ; membrane dynamics
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