Differentiation between the terms “Pannonian Basin” and “Pannonian Plain” is not clear enough in geographical literature. The paper discusses the usage of the term “plain” in geomorphology, as well as the usage of a quantitative method for plain delineation, through calculation of relief roughness coefficient (using a digital elevation model). Qualitative analysis, which includes the definition of dominant geomorphological processes and the distribution of Quaternary sediments, is an addition to the quantitative analysis. In the Republic of Serbia, the area of the Pannonian plain defined in this way is 24,448 km2, which is 27.5% of the total territory of the country. The paper gives the overview of the geotectonic structure and evolution of the Pannonian Basin System, with special stress on the territory of Serbia, as well as the chronology of the Pannonian sedimentation area in Serbia from the Lower Miocene till present. In order to explain the status of the Pannonian plain as one of the morphostructural units of Serbia, the theoretical basics of morphostructures are discussed, as well as the principles of their spatial definition and the relation to the notion of a geological structure. [Projekat Ministarstva nauke Republike Srbije, br. 47007]