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标题：Fast and Convenient Synthesis of Amine-Terminated Polylactide as a Macroinitiator for <svg style="vertical-align:-0.18pt;width:15.525px;" id="M1" height="10.7" version="1.1" viewBox="0 0 15.525 10.7" width="15.525" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7)"> <g transform="translate(72,-63.44)"> <text transform="matrix(1,0,0,-1,-71.95,63.67)"> <tspan style="font-size: 17.93px; " x="0" y="0">𝝎</tspan> </text> </g> </g> </svg>-Benzyloxycarbonyl-L-Lysine-<i >N</i>-Carboxyanhydrides
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作者：Mingjie Ju ; Feirong Gong ; Shujun Cheng 等
期刊名称：International Journal of Polymer Science
印刷版ISSN：1687-9422
电子版ISSN：1687-9430
出版年度：2011
卷号：2011
DOI：10.1155/2011/381076
出版社：Hindawi Publishing Corporation
摘要：Amine-terminated poly (L-lactide) (NH2-PLLA) with various chain lengths were successfully synthesized by sequential tert-butyl-N-(3-hydroxypropyl) carbamate initiated bulk ring-opening polymerization (ROP) of L-lactide (L-LA) in the presence of Stannous(II) 2-ethylhexanoate (Sn(Oct)2) and deprotection of the N-tert-butoxycarbonyl (Boc) group at the end of the polymer chain. The polymers obtained were characterized by FT-IR, 1H NMR, and GPC method. NH2-PLLA thus prepared was used to initiate the polymerization of ω-benzyloxycarbonyl-L-lysine-N-carboxyanhydride (Lys (Z)-NCA), and the result confirmed the high nucleophilicity of the terminal amine group. This method was not only suitable for the preparation of low molecular weight NH2-PLLA, but also quite efficient in the synthesis of high molecular weight samples.