文章基本信息

标题：An Efficient Therapy Strategy under a Novel HIV Model
本地全文：下载
作者：Chunming Zhang ; Xiaofan Yang ; Wanping Liu 等
期刊名称：Discrete Dynamics in Nature and Society
印刷版ISSN：1026-0226
电子版ISSN：1607-887X
出版年度：2011
卷号：2011
DOI：10.1155/2011/828509
出版社：Hindawi Publishing Corporation
摘要：By incorporating the chemotherapy into a previous model describing the interaction of the immune system with the human immunodeficiency virus (HIV), this paper proposes a novel HIV virus spread model with control variables. Our goal is to maximize the number of healthy cells and, meanwhile, to minimize the cost of chemotherapy. In this context, the existence of an optimal control is proved. Experimental results show that, under this model, the spread of HIV virus can be controlled effectively.