首页    期刊浏览 2024年12月12日 星期四
登录注册

文章基本信息

  • 标题:Characteristics of reactive oxygen metabolites in serum of early teenagers in Japan
  • 本地全文:下载
  • 作者:Terumi Kogawa ; Miya Nishimura ; Shizuka Kurauchi
  • 期刊名称:Environmental Health and Preventive Medicine
  • 印刷版ISSN:1342-078X
  • 电子版ISSN:1347-4715
  • 出版年度:2012
  • 卷号:17
  • 期号:5
  • 页码:364-370
  • DOI:10.1007/s12199-011-0261-7
  • 语种:English
  • 出版社:Springer Japan
  • 摘要:Objectives

    The relationship between the incidence of cardiovascular disease and the state of oxidative stress in blood has been studied to some extent. Several lines of evidence underscore the importance of primary prevention of cardiovascular disease beginning in childhood. However, little is known about the current state of oxidative stress in childhood. This study was carried out to determine the current state of the level of reactive oxygen metabolites (ROM) in serum of early teenagers.

    Methods

    This study enrolled 595 healthy junior high school students from the town of Nanbu located in northern Japan. Oxidative stress was evaluated by measuring the serum level of ROM, and antioxidant capacity was evaluated by measuring the serum level of biological antioxidant potential (BAP).

    Results

    Although the ROM level in female students [308.6 ± 63.1 Carratelli units (U.CARR)] was slightly higher than that in males (299.9 ± 55.2 U.CARR), the difference was not statistically significant. The BAP level in males was significantly higher than that in females. The levels of ROM and BAP detected in males in the first grade were higher than those in the other grades. In females, only first-graders’ BAP was higher than that in other grades.

    Conclusions

    The current study found that the ROM level in males was negatively correlated with grade. These results suggest the presence of factor(s) that increase oxidative stress in Japanese puberty.

  • 关键词:Oxidative stress ;Gender ;Healthy puberty ;Primary prevention
国家哲学社会科学文献中心版权所有