文章基本信息

标题：Development of Curcumin Based Ophthalmic Formulation
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作者：D. Anjana ; K. A. Nair ; N. Somashekara 等
期刊名称：American Journal of Infectious Diseases
印刷版ISSN：1553-6203
出版年度：2012
卷号：8
期号：1
页码：41-49
DOI：10.3844/ajidsp.2012.41.49
语种：English
出版社：Science Publications
摘要：Problem statement: Ophthalmic drug delivery system has been a major challenge due to the distinctive and unique anatomy of the eye. The use of phytochemicals for the application in ocular disease has not been investigated much, due to poor pharmacokinetics of phytochemical and hence poor therapeutic efficacy. Approach: Curcumin is one such phytochemical known for its medicinal properties, but its usage has been limited due to its poor bioavailability. Therapeutic ocular application of curcumin for indications such as allergic conjunctivitis and use of nanotechnology based delivery system for increasing its bioavailability haven
关键词：Critical Micellar Concentration (CMC); Hydrophilic Lipophilic Balance (HLB); HLB values; Drug delivery; anatomical factors; ophthalmic drug; medicinal properties; ophthalmic therapeutic; nanoemusified formulation