文章基本信息

标题：Variability of morphometric parameters of human trabecular tissue from coxo-arthritis and osteoporotic samples
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作者：Franco Marinozzi(a) ; Andrea Marinozzi(b) ; Fabiano Bini(a) Francesca Zuppante(a) 等
期刊名称：Annali dell'Istituto Superiore di Sanita
印刷版ISSN：0021-2571
出版年度：2012
卷号：48
期号：01
出版社：Editrice Kurtis Srl
摘要：Morphometric and architectural bone parameters change in diseases such as osteoarthritis and osteoporosis. The mechanical strength of bone is primarily influenced by bone quantity and quality. Bone quality is defined by parameters such as trabecular thickness, trabecular separation, trabecular density and degree of anisotropy that describe the micro-architectural structure of bone. Recently, many studies have validated microtomography as a valuable investigative technique to assess bone morphometry, thanks to micro-CT non-destructive, non-invasive and reliability features, in comparison to traditional techniques such as histology. The aim of this study is the analysis by micro-computed tomography of six specimens, extracted from patients affected by osteoarthritis and osteoporosis, in order to observe the tridimensional structure and calculate several morphometric parameters.
关键词：microtomography, bone morphometry, osteoarthritis, osteoporosis.