文章基本信息

标题：Dietary Phospholipids and Intestinal Cholesterol Absorption
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作者：Jeffrey S. Cohn ; Alvin Kamili ; Elaine Wat 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2010
卷号：2
期号：2
页码：116-127
出版社：MDPI Publishing
摘要：Abstract: Experiments carried out with cultured cells and in experimental animals have consistently shown that phospholipids (PLs) can inhibit intestinal cholesterol absorption. Limited evidence from clinical studies suggests that dietary PL supplementation has a similar effect in man. A number of biological mechanisms have been proposed in order to explain how PL in the gut lumen is able to affect cholesterol uptake by the gut mucosa. Further research is however required to establish whether the ability of PLs to inhibit cholesterol absorption is of therapeutic benefit.
关键词：cardiovascular disease; cholesterol; intestine; micelle; phosphatidylcholine; phosphatidylethanolamine; phospholipid; sphingomyelin