文章基本信息

标题：Early events and mechanisms in the induction of bacterial SOS functions: analysis of the phage repressor inactivation process in vivo
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作者：C L Smith ; M Oishi
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1978
卷号：75
期号：4
页码：1657-1661
DOI：10.1073/pnas.75.4.1657
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Different inducing agents and treatments produced distinctly different kinetic patterns of inactivation of prophage repressor molecules. The different patterns were related to differences in the initial altered states of DNA that were produced. The timing of appearance of DNA degradation was correlated with the time needed for repressor inactivation. These characteristics suggest that all the inducing treatments lead to the formation of a final predegradative DNA structure(s) (probably involving scissions) that is acted on by specific DNases, including the recBC DNase, to produce the signals for the induction of prophage.