文章基本信息

标题：Effects of cholera toxin on cochlear endolymph production: model for endolymphatic hydrops
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作者：P S Roheim ; S W Brusilow
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1976
卷号：73
期号：5
页码：1761-1764
DOI：10.1073/pnas.73.5.1761
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：To evaluate a possible role for adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1 ] and adenosine 3':5'-cyclic monophosphate in the secretion of endolymph, we studied the effect of an intra-scala media injection of purified cholera toxin (an adenylate cyclase stimulant) on cochlear endolymph volume, endolymphatic potential, and endolymphatic Na and K concentrations.