文章基本信息

标题：New gene locus modifying susceptibility to certain B-tropic murine leukemia viruses
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作者：A Declève ; O Niwa ; J Kojola 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1976
卷号：73
期号：2
页码：585-590
DOI：10.1073/pnas.73.2.585
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A new gene, SRV, the dominant allele of which occurs in mice of strain C57BL, independently modifies the slope ("hitness") and level of sensitivity of the titration curves obtained when one subclass of B-tropic murine leukemia viruses is propagated on mouse embryo cells of nonpermissive Fv-1 genotypes. Replication of another subclass of B-tropic viruses is not modified with respect to hitness, and that of N-tropic viruses is not affected.