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  • 标题:Synapse formation between clonal neuroblastoma X glioma hybrid cells and striated muscle cells
  • 本地全文:下载
  • 作者:P Nelson ; C Christian ; M Nirenberg
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:1
  • 页码:123-127
  • DOI:10.1073/pnas.73.1.123
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Clonal neuroblastoma X glioma hybrid cells were shown to form synapses with cultured, striated muscle cells. The properties of the synapses between hybrid and muscle cells were similar to those of the normal, neuromuscular synapse at an early stage of development. The number of synapses formed and the efficiency of transmission across synapses were found to be regulated, apparently independently, by components in the culture medium. Under appropriate conditions synapses were found with 20% of the hybrid-muscle cell pairs examined; thus, the hybrid cells form synapses with relatively high frequency.
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